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CVRC Events

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Rhode Island Hospital awarded $7.36 Million Grant for Cardiovascular Research

Rhode Island Hospital’s Cardiovascular Research Center (CVRC) has been awarded a $7.36 million research project grant (R01) from the National Heart, Lung and Blood Institute of the National Institutes of Health to study sudden cardiac arrest. The research will be focused on mechanisms to develop new therapies and strategies to prevent sudden cardiac arrest and to measure the impact of genetic and environmental factors on risk for sudden cardiac death. The grant will be paid out over five years and is the largest grant of its kind to be paid to a Lifespan partner hospital.

The grant is an R01 grant, the original and oldest grant mechanism used by the National Institutes of Health.

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Rhode Island Hospital Studies Uncover Keys in Sudden Cardiac Death

Researchers in Rhode Island Hospital's Cardiovascular Research Center have published two new studies focusing on the causes of arrhythmia and sudden cardiac death (SCD) when a genetic disorder is present. The studies use a first-ever genetic animal model the researchers developed in 2008 to further their understanding of a genetic disorder known as Long QT Syndrome (LQTS).

The first study identified differential conditions and cellular mechanisms that can trigger SCD when LQTS is a factor, and the second study, for the first time, directly links sex hormones to the incidence of arrhythmia and SCD. Their findings are published in the Journal of Physiology and the HeartRhythm Journal.

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Cardiovascular Research Center Working to Eradicate Sudden Cardiac Death

When NBC news journalist Tim Russert died suddenly at age 58 of heart failure in 2008, public reaction ranged from shock to sorrow to fear. The premature death of this respected, seemingly healthy man also focused a spotlight on sudden cardiac death, intensifying public awareness of this issue.

Since its founding in 2005, the Cardiovascular Research Center (CVRC) at Rhode Island Hospital, in affiliation with The Warren Alpert Medical School of Brown University, has been engaged in research that seeks to unlock the mysteries of sudden cardiac death. The CVRC focuses its research on the molecular mechanisms of cardiac arrhythmias, sudden cardiac arrest, hypertrophy (heart enlargement) and heart failure.

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